NCT01506635已完成不适用
Effect of Timolol on Refractive Outcomes in Eyes With Myopic Regression After Laser in Situ Keratomileusis: A Randomized Clinical Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Spherical Equivalent
研究概览
简要总结
In this randomized controlled clinical trial, we compare the effects of timolol versus placebo for treatment of myopic regression after LASIK
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with myopic regression equal or more than 0.5 D with minimum age of 20 years,
- •cylinder ≤ -1.00 D,
- •corrected distance visual acuity (CDVA) of at least 20/40 were included.
排除标准
- •Patients with a history of previous ocular surgery,
- •keratoconus or any ectatic corneal disorder,
- •keratoconus suspect by topography,
- •preoperative corneal opacity,
- •any corneal dystrophies,
- •presence of pterygium,
- •retinal disorders,
- •collagen vascular disorders,
- •diabetes mellitus,
- •glaucoma,
- •cataract,
- •pregnancy,
- •breast feeding
- •systemic corticosteroid therapy were excluded.
研究组 & 干预措施
Control group
Placebo Comparator
included patients who received artificial tear twice a day as control group.
干预措施: Placebo (Drug)
Timolol group
Experimental
included the patients with myopic regression who received timolol 0.5% eye drop twice a day
干预措施: Timolol (Drug)
结局指标
主要结局
Spherical Equivalent
时间窗: spherical equivalent at month 6
Effect of timolol use in timolol group will be compared with placebo group at month 6. Moreover, the changes of intragroup spherical equivalent will be assessed in both group 6 months after timolol application.
次要结局
未报告次要终点
研究者
研究点 (1)
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