Comparison of the effects of blood sampling from the neonate at birth versus blood sampling from umbilical cord on the need for blood transfusion in very premature infants
Phase 3
Completed
- Conditions
- Health Condition 1: null- Extremely preterm infants after birth
- Registration Number
- CTRI/2017/04/008320
- Lead Sponsor
- Surya Childrens hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Preterm infants less than or equal to 28 weeks and/or less than or equal to 1 kg birth weight and recruited at the time of birth
Exclusion Criteria
1.History of clinical chorioamnionitis
2.Monochorionic twins/triplets/Quadruplets
3.Anomaly of the cord like true/False knots, Stricture
4.Funisitis of the cord
5.Major congenital anomalies in the infant like Gastroschisis, Exomphalos
6.Rh isoimmnisation
7. HIV positive mother
8.Hydrops fetalis
9.Cord Blood Banking
10.Placenta accreta/Marginal insertion/Battledore placenta/Velamentous insertion
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first blood transfusionTimepoint: From birth till discharge from NICU <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method Time to 30% reduction in hemoglobin,volume of blood transfused during NICU stay,IVH Grade 3 or 4,Severe hyberbilirubinemia,ROP requiring therapy,Duration of respiratory support,Duration of hospital stay,Incidence of NEC,BPD,Serum Ferritin at 6 weeks,Haemoglobin level at 4 and 6 weeks and at discharge <br/ ><br>Timepoint: From birth till discharge from NIC