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Efficacy of injectable platelet rich fibrin in tempromandibular joint disorders.

Completed
Conditions
Temporomandibular joint disorders,
Registration Number
CTRI/2022/09/045320
Lead Sponsor
Aishla Jain
Brief Summary

The study design is prospective, parallel arm randomized controlled trial to evaluate and compare the effectiveness of iPRF for relief of signs and symptoms in specific subgroups of temporomandibular disorders. The objectives of the study are to assess and compare the effect of iPRF on temperomandibular disorders in term of pain , tenderness, clicking and limited range of motion. The primary outcome measure will be assessment of pain through visual analogue scale and secondary outcome  measures will be assessment of range of mandibular motion, tenderness of masticatory muscles – by manual palpation and clicking sound.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

Patients with internal derangement of TMJ disorders classified under Wilkes stage II, III, IV and V.

Exclusion Criteria
  • Autoimmune diseases 1.Benign or malignant temporomandibular joint lesions 2.Neurological disorders, 3.
  • Blood diseases and coagulation disorders 4.
  • Allergies or anaphylactic shock.
  • History of peptic ulcers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of pain—VISUAL ANALOGUE SCALE.0 day , 14 days 30 days , 60 days , 90 days
Secondary Outcome Measures
NameTimeMethod
1) The range of mandibular motion (maximum unassisted opening (MUO), maximumassisted opening (MAO), protrusive movement (PM), right lateral excursion (RLE) and left

Trial Locations

Locations (1)

PGIMER

🇮🇳

Chandigarh, CHANDIGARH, India

PGIMER
🇮🇳Chandigarh, CHANDIGARH, India
VIDYA RATTAN
Principal investigator
9914900871
drvidyarattan@gmail.com

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