A clinical study to compare the the sedative drug combination dexmedetomidine plus ketamine and midazolam plus ketamine on patients undergoing short surgical procedures.

Phase 4

Not yet recruiting

• Conditions: Abnormal uterine and vaginal bleeding, unspecified, (2) ICD-10 Condition: K929||Disease of digestive system, unspecified, (3) ICD-10 Condition: N359||Urethral stricture, unspecified,

• Registration Number: CTRI/2021/08/035523
• Lead Sponsor: Dr Seethal Ann Sunny

Brief Summary

This study is a prospective, double blinded randomised controlled study comparing the effect of intravenous ketamine hydrochloride plus dexmedetomidine hydrochloride and intravenous ketamine hydrochloride plus midazolam hydrochloride in procedural sedation for short surgical procedures.  different drug combinations have been used for sedation in short surgical procedures. Here we tried to compare two drug combinations and try to find out a superior combination which would provide adequate sedation, hemodynamic stability and less postoperative complications.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-08-08
• Study Start: 2021-08-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Consent to participate in study ASA physical Grade 1 and 2 Patients undergoing short surgical procedures.

Exclusion Criteria

• Patients refusal.
• Pregnancy and lactating women.
• History of any significant pulmonary, cardiovascular, neurological, hepatoreanal or metabolic disease.
• chronic use or addiction to opiates or sedatives.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
we expect that dexmedetomidine plus ketamine will provide adequate depth of anaesthesia and more stable hemodynamic variables.	20 weeks

Secondary Outcome Measures

Name	Time	Method
We expect dexmedetomidine plus ketamine to provide less incidence of postoperative complications	20 weeks

Trial Locations

Locations (1)

GR Medical College Gwalior; 🇮🇳 Gwalior, MADHYA PRADESH, India

GR Medical College Gwalior

🇮🇳Gwalior, MADHYA PRADESH, India

Dr Seethal Ann Sunny

Principal investigator

9495280289

seethalannsunny92@gmail.com