ow- or high-intensity patching for lazy eye

Not Applicable

• Conditions: Amblyopia (lazy eye); Eye Diseases; Amblyopia ex anopsia

• Registration Number: ISRCTN44138928
• Lead Sponsor: niversity College London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-02-11
• Last Update Posted: 22 February 2021
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Patients attending paediatric clinics at three large Moorfields sites. City Road (Central/East London) sees ~60% of all paediatric cases, Northwick Park (North-West London) has 6.5%, and St. George’s Hospital (South-East London) 5.5% of paediatric cases
2. Aged 4-17 years
3. Able to perform crowded LogMAR acuity testing with letters (using a matching card if necessary)
4. Mild/moderate amblyopia, defined as interocular difference in vision =0.2 LogMAR, and VA worse than 0.2 LogMAR, but better than 0.7 LogMAR in the amblyopic eye after full refractive adaptation (a minimum of 18 weeks glasses wear, with proven stability (<0.075 LogMAR change in vision between two separate visits))
5. Cycloplegic refraction within the last 6 months and up-to-date glasses (if required)

Exclusion Criteria

1. Stimulus deprivation amblyopia
2. Ocular co-morbidities that would affect final visual outcomes (e.g. albinism, nystagmus, coloboma, retinal dystrophies, lens opacities, corneal dystrophies, keratoconus)
3. Previous occlusion therapy
4. Developmental/learning difficulties that preclude accurate assessment of vision

Study & Design

• Study Type: Interventional
• Study Design: Not specified