Prophylactic antibiotic in ventilator associated pneumonia
Phase 2
- Conditions
- Ventilator Associated Pneumonia.Pneumonia, unspecified
- Registration Number
- IRCT201407029855N6
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
age over 20 years; Glasgow scale of less than 9, less than 12 hours of mechanical ventilation passed; at least 48 hours under of mechanical ventilation.
Exclusion criteria: patients who admitted 48 hours before intubation in hospital; patients who received more than two doses of antibiotics before intubation; Patients who have need antibiotics for any reason; patients who are candidates for organ donation; patients with immunodeficiency; patients who are allergic to piperacillin-tazobactam.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early ventilator associated pneumonia. Timepoint: Days 1,2,3,4. Method of measurement: Chest X ray, clinical signs, microbiological study.
- Secondary Outcome Measures
Name Time Method ate ventilator associated pneumonia. Timepoint: Days 5 , 7, 10 , 14. Method of measurement: Chest X ray, clinical sign and Microbiology study.;Mortality report. Timepoint: Daily to two weeks. Method of measurement: Reviewing date of death.;Length of stay in ICU. Timepoint: Daily to two weeks. Method of measurement: Reviewing date of discharge.