Dosage Effects of Folic Acid on Blood Folates of Honduran Women

Not Applicable

Completed

• Conditions: Spina Bifida and Anencephaly

• Registration Number: NCT00207532
• Lead Sponsor: Centers for Disease Control and Prevention

Brief Summary

CDC staff at the National Center on Birth Defects and Developmental Disabilities have been working closely with a Honduras-based organization, Project Healthy Children (PNS) and the Ministry of Health, on a folic acid supplementation study among female maquila workers. Participants are divided into two groups. One group receives a 1.0 milligram pill daily while the other group receives a 5.0 milligram pill weekly. The aim of this study is to assess serum blood folate levels measured at baseline, midpoint, and endpoint of the study. Hypothesis: Folic acid (5mg)given once weekly is as effective as folic acid (1mg)given daily in raising blood folate levels.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-03
• Study Completion: 2005-06
• Status Verified: 2005-09
• Study First Submitted: 2005-09-13
• Study First Submitted QC: 2005-09-13
• Last Update Submitted: 2005-09-13
• Study First Posted: 2005-09-21
• Last Update Posted: 2005-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

minimum employment in factory 6 mths

Exclusion Criteria

• pregnant
• currently consuming folic acid
• prior birth-defect affected pregnancy
• chronic disease
• currently taking folic acid antagonist

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Trial Locations

Locations (1)

PROTEXSA; 🇭🇳 San Pedro Sula, Honduras