Diethylhomospermine (DEHSPM) for Refractory AIDS-Related Diarrhea
Phase 1
Completed
- Conditions
- DiarrheaHIV Infections
- Registration Number
- NCT00002121
- Lead Sponsor
- VA Medical Center-Gainesville
- Brief Summary
To perform preliminary clinical testing of diethylhomospermine (DEHSPM), a polyamine analogue, for refractory AIDS-related diarrhea.
Possibly, DEHSPM will reduce stool volume and frequency in patients with refractory AIDS-related diarrhea.
- Detailed Description
Possibly, DEHSPM will reduce stool volume and frequency in patients with refractory AIDS-related diarrhea.
Patients are initially hydrated for 24 hours, followed by a 3-day baseline period. They then receive intravenous infusions of DEHSPM three times per day for 3 days, followed by observation for 3 days.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Gainesville Veterans Administration Med Ctr
🇺🇸Gainesville, Florida, United States
Gainesville Veterans Administration Med Ctr🇺🇸Gainesville, Florida, United States