NCT01632059已完成不适用
Examination of ADMA (Asymmetric-dimethylarginine)-Serum Level and DDAH II (Dimethylarginine Dimethylaminohydrolase)- Polymorphism in Patients With Severe Sepsis and Septic Shock as Prognostic Value
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- ADMA serum levels
研究概览
简要总结
Examination of ADMA (Asymmetric-Dimethylarginine)-serum level and DDAH II (Dimethylarginine Dimethylaminohydrolase)- Polymorphism in patients with severe Sepsis and septic shock as prognostic value.
This study looks into ADMA as a good prognostic factor for sepsis. Further more the dependency of the ADMA level to the DDAH II polymorphisms is reviewed this study.
详细描述
Secondary targets are the mortality (28 days ICU), the length of hospitalisation in ICU and peripheral station, the severity of the illness (SAPS II score), the SOFA-score values in the progress and the procalcitonin values in the progress
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •septical shock
排除标准
- •primary cardiogenic shock
- •pregnancy
- •breastfeeding
- •non compliance
- •moribund status
结局指标
主要结局
ADMA serum levels
时间窗: 7 days
measuring of ADMA serum levels on day 1, 3, 7
次要结局
- severity of illness(28 days)
- DDAH Ii polymorphism(28 days)
- hospitalisation (ICU and peripheral)(28 days)
- 28 day mortality(28 day)
研究者
研究点 (1)
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