BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma
Not Applicable
Terminated
- Conditions
- Esophageal Cancer
- Interventions
- Other: DIBH using VC techniqueOther: DIBH using ABC technique
- Registration Number
- NCT06317272
- Lead Sponsor
- University Medical Center Groningen
- Brief Summary
The main objective of the first part of the study is to determine the most optimal method for DIBH (active breathing control vs voluntary coached) and its reproducibility. Based on these findings, one of these methods will be selected for part 2 of this study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- Histologically proven esophageal cancer of the mid or distal esophagus
- Scheduled for external-beam photon radiotherapy with curative intention.
- WHO 0-2.
- Age >= 18 years
- Written informed consent.
Exclusion Criteria
- Serious respiratory distress
- Contra-indication for fiducial marker placement
- Noncompliance with any of the inclusion criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SEQUENTIAL
- Arm && Interventions
Group Intervention Description VC DIBH DIBH using VC technique Voluntary Coached (VC) technique for deep breath inspiration hold (DIBH) ABC DIBH DIBH using ABC technique Active Breathing Controlled (ABC) technique for deep breath inspiration hold (DIBH)
- Primary Outcome Measures
Name Time Method Feasibility DIBH Week 1, 2, 3, 4, 5 during radiotherapy Breath hold maintained for \>20 seconds
Reproducibility DIBH Week 1, 2, 3, 4, 5 during radiotherapy Diaphragm dome position within 1cm of the baseline CT Target coverage \>94% of the prescribed dose (at 98% of the ITV)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UMC Groningen
🇳🇱Groningen, Netherlands