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Clinical Trials/NCT04472234
NCT04472234CompletedNot Applicable

Could the Consumption of Water From Plastic Bottles Affect the Embryo Grade and Clinical Pregnancy Rate Obtained With IVF/ICSI in Unexplained Infertility

Nefise Nazlı YENIGUL2 sites in 2 countries82 target enrollmentStarted: April 1, 2019Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
82
Locations
2
Primary Endpoint
Exposure to BPA
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Supportive Care
Masking
None

Eligibility Criteria

Ages
23 Years to 33 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •patients aged 23-33 years who underwent IVF due to unexplained infertility
  • •patients provided urine, blood, and follicle fluid (FF) samples on the oocyte retrieval day
  • •patients who did not smoke or use alcohol
  • •patients did not work in the plastic industry

Exclusion Criteria

  • •patients who underwent IVF due to low ovarian reserve or tubal factor or male factor indications
  • •patients diagnosed with endometriosis
  • •patients with freeze-all cycles
  • •women with metabolic disease (such as hypertension or diabetes mellitus)
  • •patients with a known genetic problem (male or female)

Outcomes

Primary Outcomes

Exposure to BPA

Time Frame: 6 month

Concentrations of Bisphenol A (BPA) will be quantified in the ürine, blood plasma, and follicular fluid (individual and pooled samples) by use of ELİSA test in women with unexplained infertility

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Nefise Nazlı YENIGUL
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Nefise Nazlı YENIGUL

Ph.D. Assistant Professor Department of Obstetrics and Gynecolog

Sanliurfa Mehmet Akif Inan Education and Research Hospital

Study Sites (2)

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