Efficacy and safety of Jinhu Gushen Recipe in the treatment of diabetic kidney disease: a retrospective study based on medical records
- Conditions
- Diabetic kidney disease
- Registration Number
- ITMCTR2000003616
- Lead Sponsor
- The Affiliated Hospital of Medicine College Qingdao University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Patients who meet the diagnostic criteria for type 2 diabetes in the 2017 China Type 2 Diabetes Prevention and Control Guidelines;
2. Gender is not limited, aged between 18-80 years;
3. Patients with DKD meet the diagnostic criteria for DKD, in stage III or IV in Mogensen.
1. eGFR<30 mL/min/1.73m2 (MDRD formula).
2. Patients in need of dialysis or kidney transplantation.
3. Special medication: Any kind of traditional Chinese medicine for kidney disease have been used in the past 3 months; patients who have used nephrotoxic drugs and antioxidants within the past 2 weeks, or systemically used glucocorticoid therapy.
4. Acute coronary syndrome (ACS), transient ischemic attack (TIA), stroke, decompensated heart failure, persistent ventricular tachycardia occurred within 3 months before screening.
5. Patients with a history of nephrotic syndrome or glomerulonephritis in the past 3 months, or other causes of elevated urine albumin.
6. Patients with severe liver disease (ALT and/or AST more than three times the normal value, and/or total bilirubin> 34.2µmol/L).
7. Pregnant or lactating women, allergic physique and patients allergic to the drug used in this test.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum creatinine;Urine microalbumin/creatinine;
- Secondary Outcome Measures
Name Time Method