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Jiannao Yizhi Formula combine transcranial direct current stimulation centered on prevention of the curative effect of cognitive impairment in cognitive rehabilitatio

Phase 1
Conditions
Alzheimer disease,Vascular dementia
Registration Number
ITMCTR2022000089
Lead Sponsor
Wangjing Hospital, China Academy of Chinese Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) It meets the diagnostic criteria of Vascular dementia and Traditional Chinese medicine syndrome, and the course of dementia is more than 3 months;
(2) The mini mental state assessment scale scored =26 points;
(3) Clear consciousness, able to cooperate with the inspection and participate in the training;
(4) Diagnostic criteria of traditional Chinese medicine; Refer to the syndrome differentiation of dementia in the guiding principles for clinical research of new traditional Chinese medicine (Trial) [4];
(5) Sign the informed consent form.

Exclusion Criteria

(1) Have other brain organic diseases, depression and psychosis;
(2) Patients with malignant tumor, history of drug allergy, hematopoietic coagulation dysfunction or severe cardiopulmonary dysfunction were excluded;
(3) Cognitive impairment or dementia caused by other factors, such as brain injury, Parkinson's disease, etc;
(4) Patients who cannot cooperate with the examination (such as four diagnostic instruments of traditional Chinese medicine, meridian detector, neurophysiological evaluation, etc.).

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The scale for the differentiation of syndromes of vascular dementia;Activity of Daily Living Scale;liver function examination;blood routine examination;Mini-mental state examination;kidney function examination;Vascular dementia assessment scale-cog;
Secondary Outcome Measures
NameTimeMethod
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