Effect on Interleukin-6 levels in saliva of the diabetic patients having periapical lesio
Phase 2
- Conditions
- Health Condition 1: K044- Acute apical periodontitis of pulpal originHealth Condition 2: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2024/05/067643
- Lead Sponsor
- ITS Dental College Hospital And Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients of either gender and age between 20-65 years
2. Patients with type 2 diabetes mellitus with RBS levels not more than 160 mg/dl
3. Patient with symptomatic/ asymptomatic irreversible pulpitis
4. Patients having healthy periodontal status
5. Patients consenting to participate in the study.
6. Patients with caries will be restored prior to the study.
Exclusion Criteria
1. Patients having other systemic diseases such as hypertension, cancer, Obesity, heart diseases, Alzheimer’s disease, pregnant women
2. Any use of medicaments such as anti-inflammatory or antibiotics in past 3 months.
3. Periapical lesion more than 4mm
4.Teeth with periodontal infections
5. Patients having habits like smoking, drinking alcohol etc
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To evaluate and compare the levels of IL-6 before and after the root canal treatment in healthy patients <br/ ><br>2. To evaluate and compare the levels of IL-6 before and after the root canal treatment in diabetic patients <br/ ><br>Timepoint: Baseline(on the day of onset of trial) and after 1 week(post operative)
- Secondary Outcome Measures
Name Time Method To find the effect on IL-6 due to endodontic lesionsTimepoint: Baseline(on the day of onset of trial) & after 1 week(post operative)