Maintenance Therapy of Sorafenib after Hepatic Resection for high risk recurrence hepatocellular carcinoma (MISORA)
Phase 2
Recruiting
- Conditions
- Hepatocellular Carcinoma
- Registration Number
- JPRN-UMIN000013089
- Lead Sponsor
- Department of Surgery, Kyoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
Not provided
Exclusion Criteria
1. Previous history with sorafenib within 3 months before surgery 2. Allergy with sorafenib 3. age within the childbearing range for women 4. Severe complications 5. Patients with residual tumors 6. Other active malignancies 7. Severe renal disorders 8. Severe bronchial athma 9.severe heart disease; uncontrollable hypertension 10. Uncontrollable ascites 11. History of liver transplantaion 12. Uncontrollable esophageal varix 13. History of hepatic encephalopathy 14. Receiving medical therapy affecting sorafenib 15. Receiving herbal medicine 16. HIV-related disease 17. Patients inappropriate for study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PFS
- Secondary Outcome Measures
Name Time Method TTP OS Safety