NCT01326299
Completed
Phase 2
Post Prandial Glucose Control Proof-of-Principle
ConditionsDiabetes Mellitus, Type 2
Overview
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Abbott Nutrition
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Positive AUC from 0 to 240 minutes for plasma glucose.
Overview
Brief Summary
The purpose of this study is to compare the postprandial glycemic response of subjects with type 2 diabetes when consuming a meal along with beverages containing various combinations of nutritional ingredients and fibers versus control beverage.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 21 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •type 2 diabetes
- •between 21 and 75 years of age
- •male or a non-pregnant, non-lactating female, at least 6 weeks postpartum or postmenopausal or surgically sterile
- •BMI is \> 18.5 kg/m2 and \<35 kg/m2
- •HbA1c \< 9.0%
Exclusion Criteria
- •Subject uses exogenous insulin, exenatide, or sitagliptin phosphate
- •type 1 diabetes.
- •history of diabetic ketoacidosis.
- •current infection
- •active malignancy
- •has had a significant cardiovascular event or history of congestive heart failure.
- •end-stage organ failure or post organ transplant.
- •history of renal disease.
- •hepatic disease.
- •history of gastrointestinal disorders
Outcomes
Primary Outcomes
Positive AUC from 0 to 240 minutes for plasma glucose.
Time Frame: 0 to 240 minutes
Secondary Outcomes
- Plasma glucose concentrations(0 to 240 minutes)
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Monitoring Postprandial Glycemia in Fruit SnacksBlood GlucoseNCT05961475Ocean Spray Cranberries, Inc.20
Completed
Not Applicable
Monitoring Postprandial Blood Glucose and Insulin in Fruit SnacksBlood GlucoseBlood InsulinNCT06458946Ocean Spray Cranberries, Inc.24
Completed
Phase 1
Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop TherapyPost-Prandial HyperglycemiaPost-Prandial HypoglycemiaNCT03234491Yale University15
Completed
Not Applicable
Glycemic Response in Adults With Type 2 DiabetesGlycemic ControlNCT05166200Abbott Nutrition26
Completed
Not Applicable
Postprandial Glycemic Response in Adults With Type 2 DiabetesGlycemic ControlNCT05154045Abbott Nutrition26