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Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation.

Not Applicable
Recruiting
Conditions
Pelvic Floor; Weak
Erectile Dysfunction
Premature (Early) Ejaculation
Premature Ejaculation
Interventions
Behavioral: Therapeutic exercises
Device: Perineal electromyographic biofeedback
Device: Electrical stimulation
Registration Number
NCT06425211
Lead Sponsor
Boston Medical Group
Brief Summary

The objective of this clinical trial is to evaluate the effectiveness of pelvic floor therapy for the management of erectile dysfunction and premature ejaculation in patients with erectile dysfunction and premature ejaculation. The main question to answer is:

What is the effectiveness of pelvic floor therapy (electrostimulation, biofeedback, and therapeutic exercise) for the treatment of patients with erectile dysfunction and or premature ejaculation?

Patients will:

* Have an initial consultation of pelvic floor rehabilitation before therapy.

* Be given pelvic floor therapy.

* Have a secondary consultation of pelvic floor rehabilitation after therapy.

Three intervention groups will be included: Group 1: Patients with premature ejaculation Group 2: Patients with erectile dysfunction Group 3: Patients with erectile dysfunction and premature ejaculation.

Detailed Description

The objective of this clinical trial is to evaluate the effectiveness of pelvic floor therapy for the management of erectile dysfunction and premature ejaculation in patients with erectile dysfunction and premature ejaculation.

Methodology: Pre-post study. Erectile function or intravaginal latency time will be evaluated before and after pelvic floor therapy, in three groups of patients, independently:

* Group 1: Patients with premature ejaculation

* Group 2: Patients with erectile dysfunction

* Group 3: Patients with erectile dysfunction and premature ejaculation

66 patients will be included and will receive 24 sessions of pelvic floor therapy during 12 weeks. Outcomes will be evaluated at the end of therapy (12 weeks), 3 and 6 months follow-up.

Recruitment & Eligibility

Status
RECRUITING
Sex
Male
Target Recruitment
66
Inclusion Criteria

Overall:

  • Men over 18 years of age
  • Erectile dysfunction or premature ejaculation for at least 6 months
  • Sexual activity with a heterosexual partner at least once a week
  • Signing of informed consent before the start of the study

For the premature ejaculation group:

  • Premature ejaculation according to the International Society of Sexual Medicine (ISSM) criteria
  • Premature Ejaculation Diagnosis Tool (PEDT) questionnaire score greater than 11

For the erectile dysfunction group:

  • Clinical diagnosis of primary erectile dysfunction
  • International Index Erectile Function - Erectile Function domain (IIEF-EF) score less than 26
Exclusion Criteria
  • Pharmacological treatment for erectile dysfunction or premature ejaculation in the last 3 months
  • Erection Hardness Score (EHS) greater than 3 for patients with erectile dysfunction
  • History of hypogonadism or suspected hypogonadism due to Aging Males Symptoms (AMS) score greater than 36 for patients with erectile dysfunction
  • History of pelvic radiotherapy
  • Pacemaker or cardiac arrhythmia, epilepsy
  • History of spinal cord trauma or spinal surgeries.
  • Inability to attend therapies or controls
  • Illiteracy or cognitive disability that prevents you from completing the questionnaires
  • Psychiatric, psychological disorders, or cognitive deficiencies
  • Injuries in the area of application of the therapy
  • Active pelvic organ cancer

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Premature Ejaculation + Erectile DysfunctionElectrical stimulationPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-12 Muscle workout: sessions 13-20 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Erectile DysfunctionPerineal electromyographic biofeedbackThe therapy depends if patient is classified within muscular hyperactivity or muscular hypoactivity. For muscular hypoactivity: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: Session 24 For muscular hyperactivity they will be given: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Premature Ejaculation + Erectile DysfunctionTherapeutic exercisesPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-12 Muscle workout: sessions 13-20 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Erectile DysfunctionTherapeutic exercisesThe therapy depends if patient is classified within muscular hyperactivity or muscular hypoactivity. For muscular hypoactivity: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: Session 24 For muscular hyperactivity they will be given: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Premature EjaculationElectrical stimulationPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-15 Muscle workout: sessions 16-19 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Erectile DysfunctionElectrical stimulationThe therapy depends if patient is classified within muscular hyperactivity or muscular hypoactivity. For muscular hypoactivity: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: Session 24 For muscular hyperactivity they will be given: Pelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-7 Muscle workout: sessions 8-15 Functional training: sessions 16-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Premature EjaculationTherapeutic exercisesPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-15 Muscle workout: sessions 16-19 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Premature EjaculationPerineal electromyographic biofeedbackPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-15 Muscle workout: sessions 16-19 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Premature Ejaculation + Erectile DysfunctionPerineal electromyographic biofeedbackPelvic Floor Physiotherapy assessment: session 1 Proprioceptive and Coordination Work: sessions 2-12 Muscle workout: sessions 13-20 Functional training: sessions 20-23 Final evaluation: session 24 These interventions include: Therapeutic exercises, Perineal electromyographic biofeedback, and Electrical stimulation
Primary Outcome Measures
NameTimeMethod
Change in International Index of Erectile Dysfuntion - Erectile Dysfunction domain (IIEF-EF) score12 weeks

International Index of Erectile Dysfuntion - Erectile Dysfunction domain (IIEF-EF) score change at the end of therapy. (Groups 2,3)

Change in baseline intravaginal latency time (IVLT)12 weeks

Change in baseline intravaginal latency time (IVLT) at the end of therapy. (Groups 1,3)

Secondary Outcome Measures
NameTimeMethod
Change in Premature Ejaculation Diagnosis Tool (PEDT) questionnnaire score12 weeks, 3 and 6 months follow-up.

Change in baseline PEDT questionnaire score at the end of therapy, 3 and 6 months follow-up. (Groups 1,3)

Change in Erection Hardness Score (EHS)12 weeks, 3 and 6 months of follow-up.

Increase of 1 point in the baseline EHS at the end of therapy, 3 and 6 months of follow-up. (Groups 2,3)

Change Intracavity Assessment12 weeks, 3 and 6 months follow-up.

Change in the parameters of the baseline Intracavity Assessment at the end of therapy, 3 and 6 months follow-up.

Change in baseline intravaginal latency time (IVLT) at follow-up3 and 6 months of follow-up.

Change in IVLT at 3 and 6 months of follow-up. (Groups 1,3)

Change Premature Ejaculation Perfil (PEP) score12 weeks, 3 and 6 months follow-up.

Change in baseline PEP score at the end of therapy, 3 and 6 months of follow-up. (Groups 1,3)

Side Effects12 weeks, 3 and 6 months follow-up.

Incidente of side effects related to therapy.

Change in International Index of Erectile Dysfuntion - Erectile Dysfunction domain (IIEF-EF) score at follow-up3 and 6 months of follow-up.

International Index of Erectile Dysfuntion - Erectile Dysfunction domain (IIEF-EF) score change at the 3 and 6 months of follow-up. (Groups 2,3)

Trial Locations

Locations (1)

Boston Medical Group Colombia

🇨🇴

Bogotá, Cundinamarca, Colombia

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