A Clinical trial to compare the effect of Clomiphene Citrate and Letrozole in infertile patients with Polycystic Ovarian Disease
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Infertile women with PCOS
- Registration Number
- CTRI/2018/04/013343
- Lead Sponsor
- AIIMS Academics and Research department Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
Polycystic ovarian syndrome having infertility for at least 1 year
Exclusion Criteria
1.Hypothyroidism
2.Hyperprolactinemia
3.Male factor infertility
4.Tubal infertility
5.Females using other medications known to affect reproductive functions ( oral contraceptive pills, GnRH agonists and antagonists, anti-androgens)
6.Medical morbidities ( poorly controlled type 1 or type 2 DM; undiagnosed liver disease; history of deep vein thrombosis; pulmonary embolus; cerebrovascular accident; uncontrolled hypertension; suspected cervical carcinoma, endometrial carcinoma or breast carcinoma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To Compare the endometrial thickness during ovulation induction using Letrozole and clomiphene citrate in infertile women with PCOS <br/ ><br>Timepoint: Day 11 to day 18 of cycle
- Secondary Outcome Measures
Name Time Method 1. To Compare the ovulation rate <br/ ><br>2. To compare the pregnancy rate <br/ ><br>Timepoint: 1. From day 11 to day 18 of cycle <br/ ><br>2 after missed periods or menstruation