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Assessing cholinergic innervation in Parkinson*s disease using the PET imaging marker [18F]Fluoroethoxybenzovesamicol

Completed
Conditions
Parkinson
Parkinson's disease
10028037
Registration Number
NL-OMON43478
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

Control Subjects:
- Age between 45 - 65 years
- Willingness to cooperate and sign written informed consent
- No prior history of neurologic or psychiatric illness
- Able and fit enough to participate in this study;Patient Group:
- Diagnosis Parkinson*s disease
- Disease duration between 3 and 10 years.
- Age between 45 - 65 years
- Willingness to cooperate and sign written informed consent

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:
- The refusal to be informed about an unforeseen clinical finding
- Pregnant women, breast feeding
- Exhibition to a radiation dose for other reasons (e.g. participation in other research trial), exceeding the maximum annual dose.
- Anticoagulant medication, antiplatelet agents used in the 5d before the imaging visit
- Contra-indication for MRI-scanning (metal parts in the body)
- Other neurological conditions, more specifically neurodegenerative disorders and brain lesions.
- Treatment with deep brain stimulation

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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