Protocol for the donation of samples by volunteers for laboratory research
- Conditions
- Healthy volunteers and patient volunteers of all conditionsNot Applicable
- Registration Number
- ISRCTN13109642
- Lead Sponsor
- Medicines Evaluation Unit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 2000
1. Able to give written informed consent
2. Males and females aged over 18 years
3. Procedure specific criteria
1. History of anaemia or identified by haemocue test at screening or other clinically significant haematological disorders for blood donation
2. Current acute illness
3. Pregnancy or breastfeeding
4. History of Hepatitis B/C or HIV infection or a positive test at screen if required by the specific project
5. Volunteers who have donated to the blood transfusion service in the past 4 months, if applicable (applicable for blood donation or if specified for other procedures as per project-specific exclusion criteria)
6. Suspected use of drugs of abuse or positive drug screen, if required
7. Any contraindications for nasal sampling e.g. history of epistaxis, nasal defects, as assessed by the physician
8. Procedure-specific criteria and contraindications for performing the specific procedure
9. Any reason that the physician deems the subject not suitable to undertake the procedure(s)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sputum eosinophil counts in stable state measured using cytology at a single timepoint
- Secondary Outcome Measures
Name Time Method Sputum supernatant cytokines including IL-8 and TNF-a in stable state measured using immunoassay at a single timepoint