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临床试验/NCT02499536
NCT02499536已完成不适用

Relationship Between Intraoperative Atelectasis Findings on Transthoracic Lung Ultrasound and PaO2/FiO2

Severance Hospital2 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2015年7月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
26
试验地点
2
主要终点
Intraoperative lung ultrasound for atelectasis

研究概览

简要总结

The aim of this study is to find out relationship between PaO2/FiO2 and atelectasis finding on intraoperative lung ultrasound.

详细描述

Patients aged 20~65 with ASA class (American Society of Anesthesiologists physical status classification) 1 or 2 who are scheduled to undergo general anesthesia by using endotracheal intubation and arterial line cannulation will participate in this study. The patients with abnormal chest x-ray finding, pregnancy, arrhythmia, ischemic heart disease will be excluded from this study as well as the patients who are scheduled to undergo lung or heart surgery.

After 5 minutes preoxygenation, patients will be monitored with pulse oxymetry, noninvasive blood pressure. General anesthesia will be proceeded with typical method and endotracheal intubation and arterial cannulation will be proceeded. After ventilator adjustment (tidal volume as 8 times of the patient's ideal body weight), airway pressures(peak and plateau) will be recorded. Subsequently, arterial blood sampling will be proceeded while examination of the atelectasis findings on lung ultrasound before surgery. Lung ultrasound examination will be proceeded on 6 sections of patient's basal segments of the lung, including anterior, lateral, posterior segment. Juxtapleural consolidation, loss of A lines, presence of B lines, air bronchogram, loss of sliding sign and presence of pulse sign on lung ultrasound finding will be investigated and recorded.

Same ultrasound examination and arterial blood sampling will be followed after surgery ends.

The results of PaO2/FiO2 on arterial blood samplings will be compared with findings on lung ultrasound before and after surgery.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
20 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged 20~65
  • with ASA class 1 or 2
  • who are scheduled to undergo general anesthesia by using endotracheal intubation and arterial line cannulation

排除标准

  • The patients with abnormal chest x-ray finding,
  • pregnancy,
  • arrhythmia,
  • ischemic heart disease

结局指标

主要结局

Intraoperative lung ultrasound for atelectasis

时间窗: Baseline (Before surgery begins) and Postoperative (Just after the surgery ends)

Lung ultrasound examination for atelectasis findings (eg. whether there is a loss of A line or presence of B lines before and after surgery)

Change in PaO2/FiO2

时间窗: Baseline (Before surgery begins) and Postoperative (Just after the surgery ends)

Arterial blood sampling to find out whether their is a change in PaO2/FiO2 before and after surgery.

次要结局

  • Airway pressure change(Baseline (Before surgery begins) and Postoperative (Just after the surgery ends))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Koh, Jae Chul, MD

Department of anesthesiology and pain medicine

Severance Hospital

研究点 (2)

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