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Clinical Trials/NCT05384795
NCT05384795
Completed
Not Applicable

Perioperative Atelectasis in Patients Undergoing Orthopaedic Surgery: Prospective Cohort Study

Eric Albrecht1 site in 1 country141 target enrollmentMay 16, 2022
ConditionsAtelectasis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atelectasis
Sponsor
Eric Albrecht
Enrollment
141
Locations
1
Primary Endpoint
Lung atelectasis score
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Detailed Description

Atelectasis is one of the most common pulmonary complications in the perioperative period, occurring in 85% to 90% of patients under general anesthesia. It can be responsible for hypoxemia and be associated with postoperative pulmonary complications such as pneumonia. The consequences are a prolongation of the hospital stay and an increase in mortality. The appearance of perioperative atelectasis is mainly secondary to the induction of general anesthesia with an incidence up to 90%. The different causes are, for example, the administration of muscle relaxants, mechanical ventilation and the position of the patient. In orthopedic surgery, many procedures are performed under spinal anesthesia or under peripheral nerve block. At present, there are no studies measuring the incidence of atelectasis in patients operated under these two techniques of locoregional anesthesia, with the exception of parturients undergoing cesarean section. This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Registry
clinicaltrials.gov
Start Date
May 16, 2022
End Date
December 31, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Eric Albrecht
Responsible Party
Sponsor Investigator
Principal Investigator

Eric Albrecht

Prof. Dr. med

Centre Hospitalier Universitaire Vaudois

Eligibility Criteria

Inclusion Criteria

  • Patients over the age of 18;
  • Patients scheduled for an elective operation at the Orthopedic Hospital of CHUV;
  • Signature of the study consent

Exclusion Criteria

  • Thoracic deformities preventing the performance of pulmonary ultrasound (dressings, drains, fractures, etc.);
  • Refusal to participate;
  • Patient does not speak French.
  • Inability to discern

Outcomes

Primary Outcomes

Lung atelectasis score

Time Frame: immediately after the surgery

Atelectasis score based on validated ultrasound quantification (comparing different anesthesia techniques)

Secondary Outcomes

  • Lung atelectasis score(Four timepoints: at baseline, immediatly before surgery (after anesthesia induction), immediately after the surgery, and at the recovery room)

Study Sites (1)

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