Effect of n-3 LCPUFAs on Weight Reduction and Metabolic Syndrome.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Markers of the metabolic syndrome. Blood pressure, insulin sensitivity, HDL-cholesterol and triacylglycerol.
研究概览
简要总结
The aim of the study is to investigate if dietary fish oil has a beneficial effect on blood pressure, insulin sensitivity, blood lipid profile, body composition and metabolic rate in healthy, but slightly overweight, teenage boys.
We hypothesized that the n-3 long chain polyunsaturated fatty acids from fish oil might have greater effect during growth and development, as intervention trials studying the effect of fish oil on babies have shown greater effects than in adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 13 Years 至 15 Years（Child）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Weight above the 90th percentile for height and age.
排除标准
- •Smoking, severe illnesses.
研究组 & 干预措施
Fish oil
Daily dose = 6g fish oil baked into rye bread and wheat rolls. Participants were asked to consume two slices of rye bread and one wheat roll pr day. The fish oil was micro-incapsulated.
干预措施: Dietary oils (fish, vegetable oil) (Dietary Supplement)
Vegetable oil (Mix of canola, palm and soy oil)
Daily dose = 6g vegetable oil baked into rye bread and wheat rolls. Participants were asked to consume two slices of rye bread and one wheat roll pr day.
干预措施: Dietary oils (fish, vegetable oil) (Dietary Supplement)
结局指标
主要结局
Markers of the metabolic syndrome. Blood pressure, insulin sensitivity, HDL-cholesterol and triacylglycerol.
时间窗: Intervention period = 16 weeks
次要结局
- Body composition(16 weeks)
研究者
AAstrup
Professor
University of Copenhagen