Metacognitive therapy for those at high risk of developing psychosis

Not Applicable

Completed

• Conditions: At Risk Mental State (at risk of psychosis); Mental and Behavioural Disorders

• Registration Number: ISRCTN53190465
• Lead Sponsor: Greater Manchester Mental Health NHS Foundation Trust

Brief Summary

2020 results in https://doi.org/10.3389/fpsyg.2019.02741 (added 04/02/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-10-30
• Study Start: 2019-02-06
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. Have an identified case manager
2. In contact with mental health services
3. Meet entry criteria for an Early Detection and Intervention Team (for those at high risk of developing psychosis) operationally defined using the CAARMS
4. Judged by their clinician/case manager to be clinically stable for at least the previous 4 weeks

Exclusion Criteria

1. Moderate to severe learning disability
2. Evidence of clear organic neurological impairment (e.g., head injury or dementia)
3. Non-English speaking in so far as this would prevent the use of standardised assessment instruments
4. Inpatient/acute care required immediately prior to or during baseline assessment
5. Taking prescribed antipsychotic medication
6. Absence of case management
7. Primary diagnosis of substance dependency

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Recruitment, measured by number of referrals and number consenting at the baseline<br> 2. Retention, measured by percentage follow-up and questionnaire response rates after 3 and 6 months<br>

Secondary Outcome Measures

Name	Time	Method
<br> All measures were administered at the end of treatments (3 months post baseline) and at a 6 month follow-up:<br> 1. At risk symptoms (psychotic-like experiences), assessed using the Comprehensive Assessment of At Risk Mental States (CAARMS)<br> 2. Anxiety and depression, assessed using the Hospital Anxiety and Depression Scale (HADS)<br> 3. Metacogntions, assessed using the Metacognitions Questionnaire 30 (MCQ30)<br> 4. Hypothetical interpretations of voices, assessed using the Interpretation of Voices Inventory (IVI)<br> 5. Beliefs about paranoia, assessed using the Beliefs About Paranoia Scale (BAPS)<br> 6. Worry, assessed using the Anxious Thoughts Inventory<br> 7. Cognitive attention, assessed using the The Cognitive Attention Syndrome Scale (CAS1)<br>