Recurrent Salivary Gland Infections in Covid-19

Active, not recruiting

• Conditions: Recurrent Salivary Gland Infections in Covid-19

• Registration Number: NCT05890547
• Lead Sponsor: Benha University

Brief Summary

The aim of this study is to find out the role of Covid-19 in salivary gland infection and its recurrence.

Detailed Description

This is a prospective clinical study of 60 patients. The study will be performed in the Otolaryngology department, Faculty of Medicine, Benha University during the duration from June 2023 to December 2023.

Inclusion criteria:

Adult patients aged ≥18 years.

Exclusion criteria:

* Patients with known autoimmune diseases,

* Diabetes Mellitus

* History of cancer in the region of the head and neck or previous radio and/or chemotherapy.

* History of facial nerve palsy,

* Oral and dental diseases including chronic sialadenitis or sialolithiasis.

* previous oral surgery.

Patients were divided into two equal groups each of 30 patients according to the cause of infection. Group (1) comprises 30 patients with Covid-19 infection representing the study group COVID-19 diagnosis will be based on a positive SARS-CoV-2 nasopharyngeal swab on real-time reverse transcription-polymerase chain reaction (RT-PCR) in the presence of clinical and/or radiological signs and group (2) comprises of 30 patients with non-Covid-19 infection as a control group.

All patients will be submitted to full ENT and intraoral clinical examination. We will Compare both groups as regards patients' characteristics, risk factors, etiology, symptoms, and rate of recurrence of sialadenitis.

Study Timeline

• Status Verified: 2023-06
• Study Start: 2023-06-01
• Study First Submitted: 2023-06-02
• Study First Submitted QC: 2023-06-02
• Last Update Submitted: 2023-06-02
• Study First Posted: 2023-06-06
• Last Update Posted: 2023-06-06
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Adult patients aged ≥18 years with a history of CIVID-19 infection in the study group and of similar age without a history of COVID-19 infection.

Exclusion Criteria

• Patients with known autoimmune diseases,
• Diabetes Mellitus
• History of cancer in the region of the head and neck or previous radio and/or chemotherapy.
• History of facial nerve palsy,
• Oral and dental diseases including chronic sialadenitis or sialolithiasis.
• previous oral surgery.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
occurrence or recurrence of sialoadenitis	6 months	Compare both groups as regards patients' characteristics, risk factors, etiology, symptoms, and rate of recurrence of sialadenitis.

Trial Locations

Locations (1)

Benha university hospitals; 🇪🇬 Banhā, Egypt