Stereotactic Body Radiotherapy for Ventricular Tachycardia (CARDIAC SBRT)
- Conditions
- Ventricular Tachycardia (VT)Cardiovascular - Other cardiovascular diseases
- Registration Number
- ACTRN12622001080718
- Lead Sponsor
- Metro South Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 10
Documented sustained ventricular tachycardia (VT) with at least 3 episodes of VT in 12 months prior to enrollment
Require at least 1 anti-arrhythmic medication
Failed at least 1 invasive catheter ablation procedure, or have contraindications to invasive catheter ablation
Assessed as able to tolerate radiotherapy planning, immobilisation and treatment as deemed by the radiation oncologist
Willing and able to provide informed consent
Previous radiotherapy to the chest with any radiation dose to the heart
Advanced heart failure (NYHA Class IV)
High-volume myocardial scar substrate to such an extent that treatment with Stereotactic Body Radiotherapy (SBRT) is deemed unsafe by the radiation oncologist
Ventricular Tachycardia (VT) deemed not to be related to a definable myocardial scar
Competing comorbidities (unrelated to VT) which limit life expectancy to less than 6 months.
Must not be pregnant and/or breastfeeding if female; must have a negative pregnancy test within 7 days of study enrollment.
Implantable Cardiac Defibrillator (ICD) implanted less than 6 weeks prior
Renal failure or allergy precluding administration of Intravenous (IV) gadolinium
Computer Tomography (CT) IV contrast allergy
Any concurrent anti-neoplastic therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method