Massive Nasal Bleeding in Patients With Nasopharyngeal Carcinoma Received Curative Radiotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,327
- 试验地点
- 1
- 主要终点
- Massive Nasal Bleeding Rate
研究概览
简要总结
To investigate the incidence, predictive markers, and survival impact of massive nasal bleeding in nasopharyngeal carcinoma (NPC) patients who received curative radiotherapy (RT) with/without chemotherapy. A total of 1327 patients with previously untreated, biopsy-proven NPC, and no distant metastasis were retrospective reviewed. Investigators analyzed the occurrence rates of massive nasal bleeding between different characteristics and tried to identify important predictive factors. Investigators compared overall survival between patients with and without massive nasal bleeding by Kaplan-Meier method.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •previously untreated, biopsy-proven NPC
- •no distant metastasis
排除标准
- •incomplete record of history or treatment
结局指标
主要结局
Massive Nasal Bleeding Rate
时间窗: From date of radiotherapy until the date of first documented massive bleeding, assessed up to 360 months
Massive Nasal Bleeding Rate among different characteristics. Massive Nasal Bleeding was defined as unique blood loss \> 300 ml or recurrent blood losses \> 100 ml.
次要结局
- Overall Survival(From date of radiotherapy until the date of last clinic visit or date of death from any cause, whichever came first, assessed up to 360 months)
研究者
Hao-Shen Cheng
Attending Physician
Taichung Veterans General Hospital