A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

Not Applicable

Completed

• Conditions: Meningitis, Cryptococcal; HIV Infections

• Registration Number: NCT00002068
• Lead Sponsor: Pfizer

Brief Summary

To compare the safety and effectiveness of fluconazole and amphotericin B, alone or in combination with flucytosine, as treatment for acute cryptococcal meningitis.

Detailed Description

Not available

Study Timeline

• Status Verified: 1990-02
• Study First Submitted: 1999-11-02
• Study First Submitted QC: 2001-08-30
• Study First Posted: 2001-08-31
• Last Update Submitted: 2005-06-23
• Last Update Posted: 2005-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Trial Locations

Locations (8)

Christiana Hosp / Med Ctr of Delaware; 🇺🇸 Wilmington, Delaware, United States

Univ of Tennessee; 🇺🇸 Memphis, Tennessee, United States

Davies Med Ctr; 🇺🇸 San Francisco, California, United States

Univ of South Florida; 🇺🇸 Tampa, Florida, United States

Univ of Maryland / Inst of Human Virology; 🇺🇸 Baltimore, Maryland, United States

Harlem AIDS Treatment Group / Harlem Hosp Ctr; 🇺🇸 New York, New York, United States

Henry Ford Hosp; 🇺🇸 Detroit, Michigan, United States

Saint Michael's Hosp; 🇨🇦 Toronto, Ontario, Canada