NCT03784833UnknownNot Applicable
A Registry Study of Biomarkers in Heart Failure
Beijing Institute of Heart, Lung and Blood Vessel Diseases1 site in 1 country5,000 target enrollmentStarted: June 2016Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 5,000
- Locations
- 1
- Primary Endpoint
- Number of death (all cause)
Study Overview
Brief Summary
The registry study aims to discover the prognostic value of bio-markers in heart failure
Detailed Description
The purpose of this study is to investigate the prognostic value of biomarkers in Heart Failure.Patients with confirmed diagnosis of heart failure are enrolled.The primary outcome is all-cause mortality based on the death certificates. The secondary outcome is readmission for heart failure and all-cause mortality/readmission for heart failure according to the patients' medical records.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age greater than or equal to 18 years at the time of admission to the hospital
- •With symptoms of new-onset or worsening heart failure
- •Received or is eligible to receive a principal hospital discharge diagnosis of HF
- •With signs and syndromes as follows: dyspnea at rest or with minimal exertion (dyspnea, orthopnea, or edema)；Rales, peripheral edema, ascites, or pulmonary vascular congestion on chest radiography.
- •Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken;
Exclusion Criteria
- •Have objective evidence of cardiac dysfunction documented either by plasma concentrations of BNP and/or N-terminal pro-brain natriuretic peptide (NT-proBNP) <35 pg/mL or <125 pg/ml, respectively
- •Current known inability to follow instructions or comply with follow-up procedures.
- •Eligible patients without informed consent form
Outcomes
Primary Outcomes
Number of death (all cause)
Time Frame: 2 years of follow-up
Number of death within 2 years of discharge
Secondary Outcomes
- Number of rehospitalizations for acute heart failure (HF)(2 years of follow-up)
- Number of death ( all cause) or readmission for heart failure(2 years of follow-up)
Investigators
Study Sites (1)
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