Comparative study of analgesic efficacy between addition of dexmedetomidine or magnesium sulphate with Ropivicaine in Quadratus lumborum block for endoscopic Inguinal Hernia Repair.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- VAS score will be monitored
研究概览
简要总结
After obtaining the institutional ethical committee approval and written informed consent from the participants, they will be enrolled into our study.
A total of 90 participants will be enrolled and randomized into two equal groups of 30 each.
Group A (ROPIVICAINE WITH MAGNESIUM SULPHATE):
Ultrasound guided QL2 block with 30ml of Inj. Ropivacaine 0.375% +Inj .Magnesium sulphate 400mg
Group B (ROPIVICAINE WITH DEXMEDETOMIDINE):
Ultrasound guided QL2 block with 30ml of Inj. Ropivacaine 0.375% + Inj.Dexmedetomidine 50mcg
CONTROL GROUP C (ROPIVICAINE):
Ultrasound guided QL2 block with 30ml of Inj.Ropivicaine 0.375%
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 56.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having uncomplicated inguinal hernia -Age more than 18- 56 years.
- •American society of Anaesthesiologists grade I and II patients -Written and informed consent.
排除标准
- •Patient with known coagulopathy.
- •Patients allergic to the study drug.
- •Patients with hepatic or renal dysfunction.
- •Patients with history of receiving anticoagulant treatment.
- •Patients having history of chronic opioid consumption.
结局指标
主要结局
VAS score will be monitored
时间窗: Post procedure outcomes are assesed at 0min, 15 minutes, 1 hour, 2 hours,6hours, 12 hours, 24 hours post-operatively.
次要结局
- Time for requirement of first rescue analgesia will be noted.(Post procedure rescue analgesia assesed till 24 hours)
研究者
Keshav Ram S
Institute Of Medical Sciences