A study to compare and evaluate the analgesic efficacy of erector spinae block and anterior quadratus lumborum block using levobupivacaine in renal surgeries.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare the efficacy of erector spinae plane block and anterior quadratus lumborum block using levobupivacaine in renal surgeries
研究概览
简要总结
This prospective, randomized, double-blinded, controlled clinical study aims to compare and evaluate the analgesic efficacy of erector spinae plane block (ESPB) and anterior quadratus lumborum block (QLB) using 0.25% levobupivacaine in patients undergoing elective renal surgeries under general anaesthesia. A total of 50 patients (ASA I–III, aged 18–60 years) will be randomly allocated into two groups: Group E will receive ultrasound-guided ESPB with 25 ml of 0.25% levobupivacaine, and Group Q will receive ultrasound-guided QLB3 with 25 ml of 0.25% levobupivacaine.
The primary objective is to compare the postoperative analgesic efficacy of ESPB and QLB using Visual Analogue Scale (VAS) scores. Secondary objectives include evaluating the time to first rescue analgesia, total analgesic requirement in the first 24 hours, and incidence of complications such as nausea, vomiting, hypotension, and hematoma.
The study will be conducted in the Department of Anaesthesiology, School of Medical Sciences & Research, Sharda University, Greater Noida, over a period of 18 months (May 2025 – November 2026). Data will be statistically analysed using SPSS v25.0, with a p-value <0.05 considered significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
入选标准
- •ASA 1 to 3 Both Gender Elective Renal Surgeries under General Anaesthesia Age 18 to 60 Patients able to understand and rate their pain according to visual Analouge Scale Patient giving consent for block.
排除标准
- •Pregnant females Patients having history of drug allergy to levobupivacaine Patient having history of significiant respiratory or cardiovascular or hepatic or endocrine and psychiatry disease Patient not giving consent for performing block BMI more than 35 per metre square.
结局指标
主要结局
To compare the efficacy of erector spinae plane block and anterior quadratus lumborum block using levobupivacaine in renal surgeries
时间窗: 24 hours post operative period
次要结局
- To record the timing of first rescue analgesia and total requirement of rescue analgesia(To measure incidence of complications such as)
- Time of requirement for first rescue analgesia in post operative period.(Total amount of rescue analgesia consumed in first 24 hours)
研究者
Dr Anurag Narwal
School of medical sciences and research