The Hybrid Combination of CCTA and SPECT and CAG for Evaluation Prognosis of CAD: an Observational Follow-up Study

Completed

• Conditions: Coronary Disease

• Registration Number: NCT04554134
• Lead Sponsor: The First Affiliated Hospital with Nanjing Medical University

Brief Summary

A total of 550 patients with stable angina (40-70% stenosis) tested by coronary CT angiography (CCTA) and single photon emission computed tomography (SPECT) and coronary angiography (CAG) within 3 months were retrospectively recruited from 2005 to 2015 and follow up to 5 years. A new hybrid software was used to analysis the image data.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-01-01
• Primary Completion: 2015-01-01
• Study Completion: 2020-02-01
• Status Verified: 2020-09
• Study First Submitted: 2020-09-14
• Study First Submitted QC: 2020-09-17
• Study First Posted: 2020-09-18
• Last Update Submitted: 2020-09-24
• Last Update Posted: 2020-09-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 550

Inclusion Criteria

1. Age: 18-70
2. Gender: All
3. coronary artery disease patients (CAD)
4. underwent CCTA, SPECT and coronary angiography (CAG) together within 3 months
5. Time: 2005-2015

Exclusion Criteria

1. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), congenital heart disease (CHD), atrial fibrillation (AF), ventricular tachycardia (VT)
2. Prior coronary revascularization;
3. permanent pacemaker or internal defibrillator
4. prosthetic heart valve
5. coronary image lose
6. coronary artery severe calcification
7. motion artifacts and poor CCTA image quality

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse cardiac events (MACE)	5 YEARS	All-cause death, cardiac death, ischemic stroke, unplanned revascularization and nonfatal myocardial infarction