Surface electromyography of the diaphragm on the intensive care unit: A pilot study

Completed

• Conditions: diaphragm weakness; intensive care unit acquired weakness; 10029317

• Registration Number: NL-OMON40797
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

Informed consent
Age 18 years
Expected duration of mechanical ventilation for * 48 hours

Exclusion Criteria

(Suspected) neuromuscular disease (other than ICU-AW) or cervical spinal cord injury
Known phrenic nerve injury
Contraindication for electrode placement (e.g. severe skin infection at electrode site)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* Feasibility<br /><br>* Correlation of transcutaneous sEMG of the diaphragm with EAdi signal of<br /><br>NAVA catheter.<br /><br>* Correlation of transcutaneous sEMG of the diaphragm with airway pressure and<br /><br>flow to detect patient * ventilator dyssynchrony<br /><br>* Changes in sEMG signals during increased physical activity<br /><br>* Correlation of sEMG fatigue parameters with clinical parameters of fatigue<br /><br>during weaning from mechanical ventilation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>* Weaning failure parameters<br /><br>* Patient experience of respiratory fatigue and nurses* estimate of respiratory<br /><br>fatigue of the patient </p><br>