Transcranial Direct Current Stimulation to Treat Major Depressive Disorder

Phase 2

Completed

• Conditions: Major Depressive Disorder
• Interventions: Procedure: transcranial direct current stimulation

• Registration Number: NCT01149889
• Lead Sponsor: University of Sao Paulo

Brief Summary

The investigators purpose is to offer active Transcranial Direct Current Stimulation (tDCS) in patients of the investigators previous study who received either placebo or sertraline and have not responded.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2010-06-22
• Study First Submitted QC: 2010-06-23
• Study First Posted: 2010-06-24
• Primary Completion: 2011-09
• Status Verified: 2011-12
• Study Completion: 2011-12
• Last Update Submitted: 2011-12-02
• Last Update Posted: 2011-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
active stimulation	transcranial direct current stimulation	In active stimulation, the anode is placed over the left dorsolateral prefrontal cortex and the cathode is placed over the right prefrontal cortex. They are located five centimeters ventrally of the primary motor area, which are located five centimeters laterally of the central point of the scalp (which is located on the intersection of the sagittal and median curves). The device will deliver a charge of 2mA for 30 minutes.

Primary Outcome Measures

Name	Time	Method
Treatment Response	Week 1	Response is defined as MADRS \<=12 or less than 50% of baseline MADRS (Montgomery Asberg depression rating score).
Treatment response	Week 2	Response defined as above.

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 Sao Paulo, SP, Brazil