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Placebo Effects on Blood Pressure Induced by Expectancy Manipulation

Not Applicable
Completed
Conditions
Blood Pressure
Interventions
Drug: Histaminum hydrochloricum globuli
Drug: Placebo globuli
Registration Number
NCT00937196
Lead Sponsor
Ludwig-Maximilians - University of Munich
Brief Summary

The objective of the present study was to examine the effects of a single placebo intervention on blood pressure and to investigate autonomic and psychological mediating mechanisms.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
45
Inclusion Criteria
  • informed consent
Exclusion Criteria
  • not meeting inclusion criteria
  • hypotension or hypertension
  • treated or untreated hypertension or hypotension
  • Severe systemic disorders (tumors, tbc, diabetes, asthma etc)
  • diseases that influence the cardiovascular or gastrointestinal system
  • intake of drugs affecting blood pressure and/or autonomic nervous system
  • pregnancy and lactation phase
  • body mass index >= 32
  • cardiovascular risk factors (diabetes, smoking)
  • drug or alcohol abuse
  • insufficient compliance
  • participation in another trial within the last three months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Histaminum hydrochloricum globuliHistaminum hydrochloricum globuliTo allow double-blind administration of the placebo pills going along with verbal suggestions of a blood-pressure-lowering effect
Placebo globuliPlacebo globuli-
Primary Outcome Measures
NameTimeMethod
Blood pressure (systolic, diastolic)minutes 1 to 30 after intervention
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Institute of Medical Psychology, Ludwig-Maximilians-University Munich

🇩🇪

Munich, Germany

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