Study the effect of vitamin D on the symptoms of urticaria
Phase 3
- Conditions
- Idiopathic chronic urticaria.Other urticaria
- Registration Number
- IRCT2017092123235N12
- Lead Sponsor
- Vice chancellor for research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Chronic urticaria affected for more than 6 weeks,
negative skin Prick test for common respiratory allergens. Patient's willingness to take medication and participate, The serum level of 25 OH vit D Should be less than 10 ng / ml
Exclusion criteria: taking Corticosteroid drug during the past week.
having Other allergic diseases and Infectious diseases and Autoimmune disease
Normal levels of vitamin D
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life. Timepoint: Befor the trial. Method of measurement: DLQI Questionnaire.;Utricaria severity. Timepoint: Befor the trial. Method of measurement: USS Questionnaire.
- Secondary Outcome Measures
Name Time Method IL-17 Exprssion. Timepoint: After the trial. Method of measurement: Real-time PCR.;IL-10 Exprssion. Timepoint: After the trial. Method of measurement: Real-time PCR.;TGF-B Expression. Timepoint: After the trial. Method of measurement: Real-time PCR.;Foxp3 expression. Timepoint: After the trial. Method of measurement: Real-time PCR.