Comparison of Short-term Mortality and Morbidity Between Parenteral and Enteral Nutrition for Adults Without Cancer: a Propensity-matched Analysis Using a National Inpatient Database
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 5,824
- 主要终点
- Mortality Calculated From Outcome Section From DPC Database at 90 Days
研究概览
简要总结
Short-term outcomes of parenteral and enteral nutrition for patients unable to eat normally were compared and analyzed.
详细描述
Data were acquired from patients selected from a national inpatient database covering 1,057 hospitals in Japan. Participants had received artificial nutrition between April 2012 and March 2013, were 20 years or older, and did not have cancer. Participants were grouped into two groups: those receiving parenteral nutrition and those receiving enteral nutrition. The investigators performed one-to-one propensity-score matching between the groups. The primary outcome measurements were mortality rates at 30 and 90 days after the start of the procedure. The secondary outcomes were post-procedural complications, pneumonia, and sepsis. The investigators analyzed survival length of stay after the procedure using a Cox proportional hazards model.
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •investigators selected participants aged 20 years or older who had undergone either parenteral nutrition by central venous port insertion or enteral nutrition by percutaneous endoscopic gastrostomy, percutaneous transesophageal gastrotubing, or ileostomy between April 1, 2012, and March 31,
- •Patients who received both gastrostomy and central venous port insertion were assigned to the gastrostomy group.
排除标准
- •investigators excluded participants who had been diagnosed with cancer.
结局指标
主要结局
Mortality Calculated From Outcome Section From DPC Database at 90 Days
时间窗: 90 days after the start of the procedure
次要结局
- Post-procedural Pneumonia(the incidence of post-procedural pneumonia occurring during hospitalization. Participants will be followed for the duration of hospital stay, an expected median of 3 weeks after procedure.)
- Post-procedural Sepsis(the incidence of post-procedural sepsis occurring during hospitalization. Participants will be followed for the duration of hospital stay, an expected median of 3 weeks after procedure.)
- Re-admission 30 Days(re-admission within 30 days of discharge.)
- Mortality Calculated From Outcome Section From DPC Database at 14 Days(14 days after the start of the procedure)
- Mortality Calculated From Outcome Section From DPC Database at 30 Days(30 days after the start of the procedure)
研究者
Sumito Ogawa
Associate Professor
Tokyo University