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临床试验/NCT04013893
NCT04013893Unknown不适用

Evaluation of Enteral Nutrition in Critically Ill Children Receiving Inotropic Support in Pediatric Intensive Care Unit

Cukurova University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2019年6月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
20
试验地点
1
主要终点
28-d mortality

研究概览

简要总结

The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.

详细描述

The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements. Early enteral nutrition will be initiated within the first 24 hours of hospitalization in critically ill children who have inotropic vasopressor and inodilator support without any problems and contraindications in gastrointestinal system functions. The energy requirement of the intubated patients will be measured by indirect calorie meter method. Schofield method will be used to calculate the daily energy needs of extubated patients. 30% of the targeted energy in the first 48 hours of hospitalization and 80% of the targeted energy in the first week will be achieved by enteral nutrition.Nutritional solutions with a concentrated formula of 1 / 1.5 will be given to patients with cardiac pulmonary or renal disease requiring fluid restriction.Patients will be followed up for vomiting, diarrhea, abdominal distention, feeding intolerance, gastric residues and gastrointestinal bleeding. If these findings develop, the patient's nutrition will be interrupted according to the clinician's assessment and enteral nutrition will be re-fed as soon as possible.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Month 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Children with normal gastrointestinal system function
  • Children receiving inotropic, vasopressor or inodilatory support

排除标准

  • Children with gastrointestinal system dysfunction
  • Children with enteral nutrition contraindicated
  • Children with metabolic disease with special nutrition

结局指标

主要结局

28-d mortality

时间窗: 28 days

To evaluate the effect of enteral feeding timing on survival

次要结局

  • Vasoactive inotrope score(During inotropic treatment)
  • Lactate(During inotropic treatment)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmet Yontem

Principal Investigator

Cukurova University

研究点 (1)

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