GLUCOVAS.

• Conditions: acute ischemic stroke; acuut herseninfarct; hyperglycemia; hyperglycemie.

• Registration Number: NL-OMON25157
• Lead Sponsor: AMC

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

1. Supra-tentorial stroke with a time of onset within 24h before presentation;

2. An acute neurological deficit measurable with the National Institute of Health Stroke Score (see appendix I, NIHSS score) ¡Ý 4 at presentation;

Exclusion Criteria

1. Signs of cerebral hemorrhage on computed tomography scan;

2. Previous history of diabetes mellitus treated with insulin;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Glycemic control. (Mean glucose throughout protocol treatment; Percentage of time spent within target range);<br /> <br>2. Hypoglycemia (glucose <3.5 mmol/L): Number of hypoglycemic events per group, Number of serious hypoglycemic events (glucose<2.2 mmol/L), Number of symptomatic confirmed hypoglycemic events.

Secondary Outcome Measures

Name	Time	Method
1. Clinical outcome (modified Rankin score) at three months;<br /><br>2. Incidence of pneumonia;<br /> <br>3. Treatment data.