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临床试验/NCT00584168
NCT00584168已完成1 期

Decreasing Morbidity After Uvulopalatopharyngoplasty With the Use of Dexamethasone - A Randomized Double Blinded Placebo Controlled Trial

University of Oklahoma2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2005年3月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
1 期
状态
已完成
入组人数
15
试验地点
2
主要终点
Quantifying patient treatment with a questionaire. Patient will rate their satisfaction with pain management.

研究概览

简要总结

This study looks at lessening the pain after a Uvulopalatopharyngoplasty (UPPP) surgery by using Dexamethasone (a corticosteroid).

详细描述

The study was designed because patients have a lot of pain after they have a UPPP. Certain drugs called steroids may lessen the pain associated from this surgery. This study uses Dexamethasone (a corticosteroid), to see if it will help reduce pain, decrease the amount of time until the patient can begin to eat or return to normal activity, or increase their satisfaction with pain management. In this study the patients will be randomized (computer chosen) to receive either the study drug (dexamethasone), or a placebo. The patient will start the day before surgery with a single pill. They will then receive the dexamethasone or a placebo twice daily for the next four days and then once daily for the next two days for a total of seven days. Afterward, they will be asked to complete a questionnaire. The five questions ask patients to access the amount of pain they have, how much of their normal diet or activity they have returned to, and how much pain medication they have taken. At the next follow-up visit they will be asked to complete another questionaire (9 questions) about the patient's satisfaction with pain management.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Candidates scheduled for UPPP surgery.
  • Able to take steroids

排除标准

  • Those patients who unable to take steroids

研究组 & 干预措施

2

Placebo Comparator

Patient will receive a placebo.

干预措施: Placebo (Drug)

1

Experimental

Patient will receive dexamethasone.

干预措施: Dexamethasone (Drug)

结局指标

主要结局

Quantifying patient treatment with a questionaire. Patient will rate their satisfaction with pain management.

时间窗: Eleven days post-operative

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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