The Effective Concentration of Lidocaine With Fentanyl in Lumbar Epidural Anesthesia for Transurethral Resection of Prostate(TURP) in Elderly Patients

Not Applicable

Completed

• Conditions: BPH( Benign Prostate Hyperplasia); TURP(Transurethral Resection of Prostate)
• Interventions: Drug: epidural block with lidocaine and fentanyl

• Registration Number: NCT01892332
• Lead Sponsor: Yonsei University

Brief Summary

Epidural lidocaine is widely used in anesthesia for urologic or lower abdominal surgery because of its rapid onset. But the epidural anesthesia using high concentration of lidocaine may cause excessive motor block and unwanted side effects such as nausea, vomiting and hypotension.

This is a study to determine the effective concentration of lidocaine with fentanyl in lumbar epidural anesthesia for transurethral resection of prostate in elderly patients.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2013-06
• Study First Submitted: 2013-06-30
• Study First Submitted QC: 2013-06-30
• Study First Posted: 2013-07-04
• Primary Completion: 2014-01
• Study Completion: 2014-03
• Status Verified: 2014-07
• Last Update Submitted: 2014-07-24
• Last Update Posted: 2014-07-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• ASA 1 -3, patients scheduled for TURP( transurethral resection of prostate) were included

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Exclusion Criteria

• Patients with any contraindication to epidural anesthesia were excluded.

  • cognitive impairment
  • coagulopathy
  • allergy to lidocaine
  • infection at the puncture site

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
lidocaine with fentanyl 75ug	epidural block with lidocaine and fentanyl	-

Primary Outcome Measures

Name	Time	Method
Determining the effective concentration of lidocaine with fentanyl in lumbar epidural anesthesia for transurethral resection of prostate(TURP) in elderly patients	A blinded Assistant assess sensory and motor blockade in a 2-min intervals up to 60 minutes.	The occurrence of sensory block up to at T 12 and motor function score of 3 or more on the modified Bromage scale were considered characteristics of a successful block. Moreover, the surgery should be concluded without any complementary analgesia to confirm the success of the anesthetic procedure.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of