A feasibility study of real-time displays of brain activity as a treatment for symptoms in Huntington's disease

Not Applicable

Completed

• Conditions: Huntington's disease; Nervous System Diseases; Huntington disease

• Registration Number: ISRCTN35734205
• Lead Sponsor: niversity College London Hospitals NHS Foundation Trust

Brief Summary

2018 Results article in https://pubmed.ncbi.nlm.nih.gov/29239063 results (added 28/01/2020) 2020 Results article in https://doi.org/10.1093/braincomms/fcaa049 (added 28/02/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-11-18
• Study Start: 2020-01-28
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1. > 18 years old
2. Pre-symptomatic gene-carriers, i.e. they will carry the HD gene, but will not have been clinically diagnosed (UHDRS diagnostic score of 4 or less) at the time of enrolment, OR
3. Early-stage 1 HD patients, i.e. patients with Total Functional Capacity (TFC) score between 11-13

Exclusion Criteria

Cannot be scanned in the MRI scanner

Study & Design

• Study Type: Interventional
• Study Design: Not specified