Comparison between Dexmedetomidine and Fentanyl for pain relief after abdominal surgeries.
Phase 4
Completed
- Conditions
- Health Condition 1: null- scheduled for hepaticojejunostomy
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
ASA Class I and II, undergoing elective hepaticojejunostomy
Exclusion Criteria
•BMI >35 kg/sq metre
•Renal or hepatic dysfunction
•Known cardiovascular disorder
•Patients on beta-blockers, on long term treatment of antipsychotic drugs
•Known allergy or senstivity to dexmedetomidine, bupivacaine or fentanyl
•Contraindication to insertion of epidural catheter (local infection, spine deformities etc.)
•Alcohol abuse, heavy smoking
•Inability to use PCEA device
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method postoperative pain and analgesic requirementsTimepoint: 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method intraoperative analgesia and hemodynamic parametersTimepoint: assessed every 5 min after start of epidural infusion for 30 min ,every 15 min till end of surgery.