Evidence-based treatment of patients with acute large bowel obstruction caused by colon cancer of the left colon: Applying a clinical decision guideline
- Conditions
- Colon cancer, malignant large bowel obstruction, stent, elderly patients.Dutch: Obstructief coloncarcinoom, stent, ouderen.
- Registration Number
- NL-OMON26596
- Lead Sponsor
- Academic Medical Centre (AMC) Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 195
Inclusion Criteria
Patients with symptomatic malignant obstruction of the left colon (including the splenic flexure, descending colon and sigmoid) caused by colonic cancer who require an urgent intervention to alleviate the obstruction.
Exclusion Criteria
- Suspicion of peritonitis due to perforation (tumour or cecum blow out).
- Patients with benign disease at pathology.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In-hospital and 30-day mortality rate in the elderly patients (≥ 70 years).
- Secondary Outcome Measures
Name Time Method - Morbidity and stoma rates.<br /><br>- The technical and clinical success rates, incidence of guidewire and stent perforation and morbidity of delayed surgery of colorectal stenting.<br /><br>- The oncologic quality of surgical resection in terms of lymph node harvest and radicality.<br /><br>- Outcome (morbidity, mortality, stoma rates, survival) of conservative, non-resectional management of patients with incurable disease or high operative risk that are treated according to the clinical decision guideline with either a colorectal stent or stoma alone.