Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- hyaline cartilage thickness assessment
研究概览
简要总结
this study will be conducted to compare between high power laser and low-intensity laser on ultrasonographic and functional outcomes in patients with knee osteoarthritis
详细描述
Osteoarthritis (OA) is a major source of pain, disability, and socioeconomic cost worldwide. The epidemiology of the disorder is complex and multifactorial, with genetic, biological, and biomechanical components. It is estimated that 63 to 85 percent of Americans over age 65 have radiographic signs of OA and that 35 to 50 percent have symptoms of pain, stiffness or limitation of motion. Between 9 and 12 percent of elderly Americans (approximately 3 million people) have enough impairment from OA that they cannot perform their major activities, and half of these individuals are totally disabled (confined to bed or a wheelchair). High power laser therapy (HPL) that involves higher-intensity laser radiation is a new, painless, and powerful modality that showed significant results in pain reduction. One of the modalities commonly used by clinicians was Low Level Laser Therapy introduced as an alternative, safe and non-invasive treatment for OA about 30 years ago.A more recent systemic review investigated the effects of low-level and high-intensity laser therapy as adjunctive to rehabilitation exercise on pain, stiffness and function in knee osteoarthritis and concluded that Both LLLT and HPL are beneficial as adjuncts to rehabilitation exercise in the management of knee OA. Based on an indirect comparison, the HPL and exercise seems to have higher efficacy in reducing knee pain and stiffness, and in increasing function. To confirm this finding, a direct comparative investigation of the two types of laser therapy may be necessary. ninety patients with knee osteoarthritis will be assigned randomly to three groups; the first experimental will receive high power laser plus conventional physical therapy, second one will receive low-intensity laser and traditional physical therapy, finally, the third group will receive traditionally therapy only
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
opaque sealed envelop
入排标准
- 年龄范围
- 45 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •X-ray stages II and III osteoarthritis
- •Age between 45 and 75 years.
- •BMI equal to or less than 35.
排除标准
- •Unwillingness to participate in the study.
- •Uncompleted evaluation/treatment programs.
- •Any damage to the knee joint during the study.
- •Using any treatment other than prescribed therapeutic protocols.
结局指标
主要结局
hyaline cartilage thickness assessment
时间窗: up to eight weeks
utrasonographe device will be used to assess hyaline cartilage thickness
osteophyte diameter
时间窗: up to eight weeks
ultrasonographe device will be used to assess the osteophyte diameter
次要结局
- knee range of motion(up to eight weeks)
- pressure pain threshold(up to eight weeks)
- knee function(up to eight weeks)
- pain intensity(up to eight weeks)
研究者
Nabil Mahmoud Ismail Abdel-Aal
principle investigator nabil mahmoud ismail abdel-aal
Cairo University
