Effect of Yoga Therapy on Hormones, Cardiac health and psychological well-being in Male Partners of Infertile Couples

Not Applicable

Registration Number: CTRI/2024/08/072037

Lead Sponsor: Dr Nirangjhana S

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Male partners of both primary and secondary infertile couple (former indicating a person who has never achieved pregnancy, and the latter when at least one previous pregnancy has been successfully attained) with normo/oligo/teratozoospermia on standard care with antioxidants/ vitamin supplements.

2. Perceived Stress Scale (PSS) score = 14

Exclusion Criteria

1. History of clinically diagnosed psychiatric disorder on medications

2. H/O recent infections (3 months)

3. H/O urogenital infections (Prostatitis, Orchitis, Epididymitis)

4. Presence of WBCs, azoospermia (no spermatozoa in the ejaculate), agglutination in semen analysis

5. Patients on hormonal therapy

6. H/O undescended testicles, testicular torsion, CBAVD (Congenital Bilateral Absence of Vas Deferens), varicocele

7. H/O erectile, ejaculatory dysfunction, spinal cord disease

8. Obesity (BMI = 30)

9. H/O hypothalamic and/or pituitary defects (hypogonadism, hypergonadism)

10. H/O Diabetes mellitus, Hypertension, thyroid disorder

11. H/O current smoking, alcohol intake, drug abuse

12. H/O lifestyle change especially eating habit in the past 3 months

13. H/O surgery, severe sprain or fracture in the past 3 months

14. H/O vertebral, disc disorders, sciatica

15. H/O yoga practice/ structured exercise practice

16. Those whose female partners have blocked fallopian tubes/ anovulation/ poor ovarian reserve/ uterine anomalies

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effect of 8 weeks yoga intervention on semen parameters, inflammatory markers, neuroendocrine hormone levels, heart rate variability, autonomic function tests and psychological parameters in male partners of infertile couples with psychological stress, in comparison to control groupTimepoint: 1 year

Secondary Outcome Measures

Name	Time	Method
a)To compare semen parameters, inflammatory markers, neuroendocrine hormone levels, heart rate variability, autonomic function tests & psychological parameters in male partners of infertile couples with psychological stress, pre yoga & post yoga intervention. <br/ ><br>b)To estimate the association of serum IL-6 with semen parameters, neuroendocrine hormones (total testosterone, DHEAS, FSH, LH, prolactin, oestradiol, cortisol) & psychological parameters in Male partners of infertile couple with psychological stress. <br/ ><br>Timepoint: 1 year