Guided biofilm therapy- A pioneering approach utilizing piezo instrumentation using erythritol compared with glycine air polishing: A randomized controlled trial.

The primary outcome is to evaluate the effectiveness of erythritol and glycine for biofilm removal by combining an air abrasive device with ultrasonic piezo instrumentation (Guided Biofilm Therapy) after initial scaling.

Thirty periodontal patients were randomly divided into two groups (n=15). Group A will be receiving erythritol-based air polishing, while Group B will be receiving glycine-based polishing. At baseline, all patients will be undergoing comprehensive periodontal examination, with Plaque Index (PI), Gingival Index (GI) will be recorded. A disclosing agent will be applied prior to treatment for targeted biofilm removal. Group A will be treated with an AIRFLOW® device using erythritol powder, and Group B with glycine powder, according to manufacturer’s protocol followed by supragingival and subgingival polishing will be performed by a single calibrated operator. Oral hygiene instructions will be given at each visit. Clinical parameters will be reassessed at 1 month and 3 months to evaluate the effectiveness of both powders in non-surgical periodontal therapy. This study hypothesizes that the gingival health condition of the patients of group A  will be superior to that of group B.