Randomised controlled trial of treating dysfunctional breathing to reduce breathlessness in severe asthma

Not Applicable

Completed

• Conditions: Respiratory: Asthma; Respiratory; Asthma

• Registration Number: ISRCTN92818360
• Lead Sponsor: Record Provided by the NHSTCT Register - 2006 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09-29
• Last Update Posted: 5 June 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

31 patients suffering from severe asthma:
1. Patients with diagnosis of asthma requiring regular maintenance medication (that includes high dose inhaled corticosteroid and long-acting ?2 agonist)
2. High medical resource usage
3. Non-smoker for at least one year
4. Historical evidence of reversibility

Exclusion Criteria

1. Previous treatment for hyperventilation, dysfunctional breathing, or other functional disorder of respiratory mechanics
2. Participation in another trial involving respiratory intervention
3. Current or recent lower respiratory tract infection
4. Presence of other respiratory diseases
5. DLCO <70% predicted, significant co-morbid illness
6. Pregnancy or nursing mother
7. Psychiatric disorder
8. Hospitalisation for asthma within the prior 6 weeks

Study & Design

• Study Type: Interventional
• Study Design: Not specified