A Study to evaluate the effect of premedication with oral pregabalin in attenuating the hemodynamic pressor response to laryngoscopy and intubatio
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/07/026382
- Lead Sponsor
- St Stephens Hospital DELHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 64
Inclusion Criteria
Patients undergoing elective surgery under general anesthesia, requiring tracheal intubation.
Exclusion Criteria
1. Patient refusal
2. Seizure disorders
3.Patients on chronic neuroleptic medications, tricyclic antidepressants or serotonin and nor epinephrine re-uptake inhibitor
4. Pregnant or breast-feeding women.
5. Anticipated difficult airway.
6. History of cardiac, pulmonary, or renal disease, Uncontrolled Diabetes or hypertension.
7. GI disturbance which hinders enteric absorption to oral medications.
8. Allergy to any anaesthetic medication and Pregabalin.
9. Duration of laryngoscopy exceeding 25 seconds or second attempt for intubation is needed.
10. Mallampati grade 3 and 4
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method attenuates the pressor response to laryngoscopy and intubationTimepoint: 15 minutes
- Secondary Outcome Measures
Name Time Method sedationTimepoint: 90 minutes