Primary Prevention With Statin and Incidence of Recurrent Myocardial Infarction and Cardiogenic Shock in Post-Acute Coronary Syndrome Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 145
- 试验地点
- 1
- 主要终点
- Cardiogenic Shock
研究概览
简要总结
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.
详细描述
Adult patients (≥ 18 years of age) with acute coronary syndrome which are diagnosed under ICD-10 coding of I24.9 were included in this study. The inclusion criteria are patients with primary diagnosis of I24.9 and with a complete record of prior medical and treatment history, electrocardiographic findings, cardiac marker results and outcomes. Participants were grouped into 2 groups - statin and non-statin based on prior history of statin use prior to ACS. Diagnosis of ACS was made based on clinical, electrocardiographic and cardiac marker findings found in the medical record.
Data such as age, sex, ethnic, education, prior medical and treatment history, electrocardiographic and cardiac enzyme results as well as outcomes were collected from the patients' medical records. Outcomes of interest were defined as either recurrent myocardial infarction, cardiogenic shock, mortality or combinations of them as diagnosed in the medical records. GRACE and TIMI Scores are calculated to predict in hospital and future mortality rates.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of Acute Coronary Syndrome
- •Presence of detail on statin prescription history
排除标准
- •Unavailability of electrocardiographic findings, cardiac marker results, GRACE and TIMI score parameters
- •Incomplete records of prior medical and treatment history
研究组 & 干预措施
Statin
History of statin use for primary prevention
干预措施: Statin (Drug)
结局指标
主要结局
Cardiogenic Shock
时间窗: Through study completion, an average of 1 year
Clinical Diagnosis of Cardiogenic Shock reported in medical records
Mortality
时间窗: Through study completion, an average of 1 year
Patient death reported in medical records
Recurrent Myocardial Infarction
时间窗: Through study completion, an average of 1 year
Clinical Diagnosis of Recurrent Myocardial Infarction reported in medical records
次要结局
未报告次要终点
研究者
Angela Felicia Sunjaya
Principal Investigator
Tarumanagara University
