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临床试验/NCT03596944
NCT03596944已完成不适用

Primary Prevention With Statin and Incidence of Recurrent Myocardial Infarction and Cardiogenic Shock in Post-Acute Coronary Syndrome Patients

Tarumanagara University1 个研究点 分布在 1 个国家目标入组 145 人开始时间: 2017年8月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
145
试验地点
1
主要终点
Cardiogenic Shock

研究概览

简要总结

This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.

详细描述

Adult patients (≥ 18 years of age) with acute coronary syndrome which are diagnosed under ICD-10 coding of I24.9 were included in this study. The inclusion criteria are patients with primary diagnosis of I24.9 and with a complete record of prior medical and treatment history, electrocardiographic findings, cardiac marker results and outcomes. Participants were grouped into 2 groups - statin and non-statin based on prior history of statin use prior to ACS. Diagnosis of ACS was made based on clinical, electrocardiographic and cardiac marker findings found in the medical record.

Data such as age, sex, ethnic, education, prior medical and treatment history, electrocardiographic and cardiac enzyme results as well as outcomes were collected from the patients' medical records. Outcomes of interest were defined as either recurrent myocardial infarction, cardiogenic shock, mortality or combinations of them as diagnosed in the medical records. GRACE and TIMI Scores are calculated to predict in hospital and future mortality rates.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of Acute Coronary Syndrome
  • Presence of detail on statin prescription history

排除标准

  • Unavailability of electrocardiographic findings, cardiac marker results, GRACE and TIMI score parameters
  • Incomplete records of prior medical and treatment history

研究组 & 干预措施

Statin

History of statin use for primary prevention

干预措施: Statin (Drug)

结局指标

主要结局

Cardiogenic Shock

时间窗: Through study completion, an average of 1 year

Clinical Diagnosis of Cardiogenic Shock reported in medical records

Mortality

时间窗: Through study completion, an average of 1 year

Patient death reported in medical records

Recurrent Myocardial Infarction

时间窗: Through study completion, an average of 1 year

Clinical Diagnosis of Recurrent Myocardial Infarction reported in medical records

次要结局

未报告次要终点

研究者

发起方
Tarumanagara University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Angela Felicia Sunjaya

Principal Investigator

Tarumanagara University

研究点 (1)

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